varfish

VarFish: comprehensive DNA variant analysis for diagnostics and research

VEP-like tool for sequence ontology and HGVS annotation of VCF files

A port of biocommons/hgvs to the Rust programming language

Genome annotation based on Rust and RocksDB

A port of biocommons/seqrepo to the Rust programming language

(Legacy) Annotate variants for import into VarFish server.

Download public databases for VarFish

Setup VarFish as using Docker Compose

VarFish REST API client (CLI + Python package)

Rust-based background worker for varfish-server

(Partial) port of biocommons/bioutils to Rust

VarFish (Snakemake) Client Workflow for Querying Snakemake

DEPRECATED Convert annotation database files to Var:fish: import format

Clinvar data builds for annonars

DEPRECATED, use https://github.com/bihealth/varfish-docker-compose instead

Automated evaluation of ACMG rules

Simple REST API wrapper for CADD-scripts

Repository for building IGSR data sets for use in VarFish

VarFish (Snakemake) Client Workflow for Validation

Re-implementation of the CADA phenotype-based prioritization algorithm