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How does the skin work?

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How does the skin work?
Your skin is your largest organ: about 2 square metres that keeps water in, germs out and your core at 37 °C. Cut open a block of it, follow a cell from birth to flake, sweat through a humid heatwave, feel with five kinds of sensor, and see why skin comes in every shade.

▶ Play with it  ·  Read the 60-second explainer  ·  Watch the 40-second video

Glassbox No. 040 The Body Code: MIT Content: CC BY 4.0 Privacy: explained

In 60 seconds

  1. Three layers, one big organ. Skin covers about 1.5 to 2 m² and weighs about 3.5 to 4 kg. On top is the thin epidermis, about 0.1 mm on most of the body. Below is the tough dermis with blood vessels, nerves, hair follicles and sweat glands, and under that a layer of fat.
  2. A wall that rebuilds itself. New cells are born in the basal layer and pushed up. They fill with keratin, die and flatten into bricks glued with fatty mortar, then flake off, about 4 weeks after birth. This barrier keeps water in and germs out.
  3. Your built-in air conditioner. Vessels widen to dump heat or narrow to save it, and each gram of sweat that evaporates carries away about 2,400 J. In humid heat sweat can't dry: near a wet-bulb temperature of 35 °C, or lower, even resting in shade can't cool you.
  4. Five kinds of touch sensor. Merkel cells feel pressure, Meissner corpuscles light touch, Pacinian corpuscles vibration near 250 Hz, Ruffini endings stretch, and free nerve endings pain and temperature. A fingertip tells two points apart at 2 to 3 mm; the back needs about 40 mm.
  5. Melanin, the skin's own sunshade. Everyone has about the same number of melanocytes; skin tone depends on how much and which melanin they make. Melanin absorbs UV. UV-B burns but also makes vitamin D. Indian summers often reach UV index 11+, and SPF 30 used thickly blocks about 97% of sunburning UV.
  6. Healing and what goes wrong. A cut heals through clotting, inflammation, new tissue and months of remodelling into a scar at most 80% as strong. Burns are graded by depth. Acne, eczema and moles each have a simple cause. For your own skin, see a doctor or dermatologist.

Words worth knowing

Term Meaning
Epidermis The thin outer layer of skin, renewed from its basal layer about every 4 weeks.
Dermis The tough middle layer of collagen and elastin, holding vessels, nerves, glands and hair roots.
Stratum corneum The outermost skin: flat dead cells of keratin glued by fats, the main barrier.
Melanin The pigment made by melanocytes that colours skin and absorbs ultraviolet light.
Eccrine gland The common sweat gland, a coiled tube opening straight onto the skin.
Latent heat The heat that turning a liquid into vapour takes: about 2,400 J per gram of sweat.
Wet-bulb temperature A single temperature that combines heat and humidity; it sets the limit for cooling by sweat.
Pacinian corpuscle An onion-like touch receptor deep in the skin, most sensitive to vibration near 250 Hz.
SPF Sun protection factor: with SPF 30 applied as in the lab, about 1/30 of sunburning UV gets through.

A short history

2,500 years from a new nose cut from the cheek in ancient India to lab-grown skin, touch sensors and a fairer scale for every skin tone.

  • 600 BCE · A new nose from the cheek (Sushruta (attributed), Ancient India)
  • 1665 · The microscope finds the layers (Marcello Malpighi, Italy)
  • 1794 · A letter from Pune (Cowasjee and an Indian surgeon; letter signed only “B.L.”, Near Pune, India; printed in London)
  • 1834 · One point or two? (Ernst Heinrich Weber, Leipzig, Germany)
  • 1869 · Pinches of skin that grow (Jaques-Louis Reverdin, Paris, France)
  • 1919 · Sunlight heals bones (Kurt Huldschinsky; Alfred Hess and Lester Unger, Berlin, Germany; New York, USA)
  • 1934 · The science of sweat (Yas Kuno, Japan and Manchuria)
  • 1946 · Glacier cream and SPF (Franz Greiter, Austria (named after Piz Buin, a peak in the Alps))

The full story, with 30 moments, charts, people and 57 sources: glassbox.how/e/skinclear/history. The data lives in history.json.

Video and slides

Made with the Glassbox studio from this box's storyboard (window.glassbox.director). Free to reuse under CC BY 4.0.

Video: How does the skin work?

Carousel slide-1 Carousel slide-2 Carousel slide-3 Carousel slide-4

File What Size
glassbox/reel.mp4 Reel / Short, with captions and soundtrack 1080×1920
glassbox/video.mp4 YouTube video, with captions and soundtrack 1920×1080
glassbox/slide-1…10.jpg Instagram carousel 1080×1350
glassbox/thumb.jpg YouTube thumbnail 1280×720
glassbox/cover.jpg Share card and repo social preview 1200×630
glassbox/history-reel.mp4 “History in 10 moments” Reel / Short 1080×1920
glassbox/history-slide-*.jpg History carousel 1080×1350
glassbox/post.json Post copy and schedule used by the publish kit

Privacy

This box has no accounts and no ads, and it ships its own fonts and libraries. When you run it yourself it sends nothing anywhere. On glassbox.how, the site's /bar.js also loads Glassbox's analytics: Google Analytics to count visits (it asks first in the EU, UK and Switzerland, and stays off when your browser sends Global Privacy Control or Do Not Track) and ClickTrust to detect bots.

It remembers a few things in your own browser only, and never sends them anywhere:

Browser storage key What it holds
skinclear.v1 Which chapters you have opened, your best quiz scores, and sound on or off.

Exactly what each one sees is at glassbox.how/privacy.

Licences

Found a mistake? Open an issue. Corrections happen in public.

Run it

It's plain HTML, CSS and JavaScript. No build step and no dependencies. Run locally, it contacts no other website.

python3 -m http.server 8000

Three.js and the fonts ship in vendor/ and fonts/, so it also works offline.

Then open http://localhost:8000.

How it's built

File What
index.html, css/app.css The page and its styles
js/app.js, js/stage.js, js/ui.js, js/kit.js The shared Glassbox 3D engine: chapters, 3D stage, controls, quiz, video director
js/chapters/*.js One file per chapter: the 3D model, controls, text, key terms, quiz and video scenes
js/skin.js The shared skin block (layers, follicles, glands, vessels, nerves, receptors), Monk skin tones, and the sweat heat-balance and wet-bulb physics
glassbox.json Title, question, explainer beats, key terms, browser storage and credits shown on glassbox.how
reel in each chapter The storyboard the Glassbox studio records into short videos
glassbox/ The published video, slides, thumbnail and post copy
fonts/, vendor/three/ Self-hosted Geist and Instrument Serif (SIL OFL 1.1) and three.js (MIT)

About

How does the skin work? An interactive, open-source explainer. Glassbox No. 040.

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